The film · 4:04
Circuits of Resilience
How chronic stress reshapes the brain's reward circuitry
Chapters
Also from the lab · 3:38
How We Model Depression
How the lab models depression in a mouse, reads the genes of a single cell type, and what those genes showed.
Chapters
Made by the Ferguson Lab. Music: AI-generated instrumental (ElevenLabs Music). Drawn by code (HTML Canvas), no stock footage.
Sources: Golden et al. Nat Protoc 2011 · Kim et al. J Neurosci 2016 · Kim et al. Mol Psychiatry 2021 · Kim et al. Biol Psychiatry 2024. Research supported by the National Institute of Mental Health.
Research stories on film
Four more short films
Each research story has its own film, on its story page.
Featured study
Ma X, Kim H, Zhang L, Chen P, Wei J, Cui Y, Chen L, Xu Y, Zhang J, Dai Z, Ferguson D, Qiu S. A nucleus accumbens-projecting prefrontal cortex circuit underlies chronic social stress-induced depression-like behaviors. Translational Psychiatry (2026).
doi:10.1038/s41398-026-04128-w
Also cited: Kim et al., Bio-protocol 2017 · J Neurosci 2016 · Mol Psychiatry 2021 · Biol Psychiatry 2024
Credits
- Production ·
- Ferguson Lab, University of Arizona College of Medicine – Phoenix
- Collaboration ·
- With the Qiu Lab (Shenfeng Qiu, MD, PhD)
- Animation ·
- Three.js
- Support ·
- Research supported by the National Institute of Mental Health (NIH)



